PECULIARITIES OF UNCONNECTED RESPIRATION IN MITOCHONDRIA AND ITS COMPARISON WITH PHOSPHORATE RESPIRATORY
Abstract
In this work, respiratory processes not associated with the synthesis of phosphorylated and ATP in various tissues of warm-blooded laboratory animals were studied. In particular, the oxidation of various substrates in tissue mitochondria is relatively organized. The material also provides information that, in contrast to NAD-dependent substrates, during the oxidation of succinate, a high oxidation rate is observed mainly in the V4 state, and the phosphorylation rate is V3. In addition, it is assumed that one of the possible reasons for the high rate of ADP-independent respiration during oxidation may be the presence in mitochondria of an uncoupled respiratory chain that does not work together with ATP synthesis.
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